Dodit Yutanto, Achmad Lefi
Coronary artery disease (CAD) is recognized as a leading cause of adult mortality worldwide. Current therapies in the treatment of CAD include drug interventions, percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) surgery, and transmyocardial laser revascularization (TMR). However, these approaches are invasive and often inadequate in the treatment of advanced CAD, and are associated with serious cardiovascular risks and complications. Cardiac shock wave therapy (CSWT) is a novel, noninvasive intervention that can ameliorate myocardial ischemia and improve cardiac function. Early clinical trials showed that CSWT alleviated angina and improved cardiopulmonary ļ¬tness in patients with myocardial ischemia. Evidence indicates that CSWT may reduce the ischemic burden and provide angina relief by promoting angiogenesis and revascularization in ischemic myocardium.
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